慢性肺性菌菌病的手术治疗:从一个单一机构进行的回顾性研究
Hajime Tamura1,2, Hidemi Suzuki3, Takahiro Yamanaka1
1Department of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuo-Ku, Chiba, 260-8670, Japan.
Surgery today
|August 9, 2023
概括
慢性肺性菌菌,虽然在亚洲很少见,但正在增加. 这个案例系列强调了六名患者的手术治疗,强调了旅行史和成像,以早期诊断这种真菌感染.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 由Coccidioides物种引起的Coccidioidomycosis是美国西南部和墨西哥北部的特有病.
- 虽然在日本和亚洲历史上很少见,但近几十年来菌菌病的发病率上升.
- 型虫的种类具有高度的传染性,需要小心处理和诊断.
研究的目的:
- 介绍一系列慢性肺性菌菌病的病例,这些病例在一个机构中进行了手术治疗.
- 审查临床表现,诊断挑战和肺部菌菌菌的手术治疗.
主要方法:
- 六名患者的回顾性图表审查,这些患者接受了肺部切除术,以肺部菌菌症为由.
- 2007年1月至2021年12月在千叶大学医院收集的数据.
- 分析旅行史,血清学,成像学和组织病理学发现.
主要成果:
- 所有六名患者都有前往美国西南部的旅行史.
- 胸部CT扫描显示,在所有病例中,都有一个单一的,明确的圆形结节.
- 切除结节的组织病理学证实了Coccidioides球状粒体的颗粒体,尽管在一些患者中进行了负面或不确定的手术前测试.
结论:
- 在有相关旅行史和特征性放射学发现的患者中,应考虑肺性皮小菌病.
- 早期的怀疑和诊断至关重要,即使最初的血清学结果是负面的.
- 在样本处理过程中采取严格的预防措施至关重要,以防止有毒性传播.
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