一个新出现的Enterococcus cecorum疫情的表征,在美国南部的一个肉集成器中引起严重的系统性疾病,同时出现腿部问题
Gunnar Dunnam1, Jay Kay Thornton1, Martha Pulido-Landinez2
1Mississippi State University, College of Veterinary Medicine, Poultry Research and Diagnostic Laboratory, 39208.
Avian diseases
|August 9, 2023
概括
Enterococcus cecorum在肉中引起全身性疾病和腿部问题,通常表现为败血症而不是典型的脊椎骨质炎. 大多数隔离体显示出显著的抗生素耐药性.
科学领域:
- 兽医病理学 兽医病理学
- 细菌学 细菌学是一门学科.
- 禽类的健康 禽类的健康
背景情况:
- 杆菌 (Enterococcus cecorum) 通常会在中引起骨髓炎.
- 新出现的报道表明,E. cecorum可以引起败血病变,并影响软骨,导致大腿骨头缩和肌炎.
研究的目的:
- 在肉爆发期间调查Enterococcus cecorum的表现.
- 分析E. cecorum分离物的抗菌素耐药性模式.
主要方法:
- 来自密西西比州立大学的100只肉病例的分析 (2021年4月至12月).
- 使用维特克 MALDI-TOF MS. 识别E. cecorum的标识.
- 用WHONET软件分析的抗菌敏感性测试.
主要成果:
- 疫情在6月至8月达到顶峰,影响15-31天 (平均21天) 的肉.
- 主要病变包括败血症,心膜炎,周肝炎,骨髓炎和关节炎.
- E. cecorum从各种部位分离出来,而不仅仅是胸椎.
- 80%的分离物对三种或更多类型的抗生素具有耐药性,耐药性模式具有很高的变异性.
结论:
- 在这次 brojiler疫情中,Enterococcus cecorum主要表现为一种感染性疾病.
- 观察到显著的抗菌素耐药性,突出显示了治疗方面的挑战.
- 需要进一步的研究来了解E. cecorum在家禽中的热带性和耐药性机制.
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