串联多聚体的普遍性及其与同步的色膜发达腺瘤的关联
Gilmara Coelho Meine1,2, Guilherme Becker Sander1
1Universidade Federal do Rio Grande do Sul, Escola de Medicina, Programa de Pós-graduação: Ciências em Gastroenterologia e Hepatologia, Porto Alegre, RS, Brasil.
Arquivos de gastroenterologia
|August 9, 2023
概括
临床上显著的状息肉 (CSSP) 和晚期腺瘤的患病率相似. CSSP增加了晚期腺瘤的风险,特别是那些位于附近的腺瘤.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜检查是指内镜检查.
背景情况:
- 状病变在多达三分之一的结直肠癌 (CRC) 之前发生,并且与间歇性CRC有共同特征.
- 之前的研究表明,有形多的流行率各不相同,与晚期腺瘤存在不一致的关联.
研究的目的:
- 为了确定有状息肉的患病率.
- 评估状息肉和同步晚期腺瘤之间的关联.
主要方法:
- 在45-75岁的患者中,对1208次结肠镜进行了回顾性分析.
- 收集了关于状多亚型和晚期腺瘤的流行率的数据.
- 进行多变量分析以评估关联.
主要成果:
- 患病率:临床上显著的状多体 (CSSP) 11.3%,大状多体 (LSP) 6%,状状腺瘤 (SSA) 3.7%.
- CSSP与同步晚期腺瘤 (OR 2.121) 相关,特别是近位腺瘤 (OR 2.966).
- LSP (OR 2.872) 和SSA (OR 5.032) 与近端先进腺瘤有关.
结论:
- CSSP和晚期腺瘤的患病率是可比的.
- CSSP是晚期腺瘤的危险因素,与近邻腺瘤的联系更强.
- LSP和SSA特别与近端先进腺瘤有关.
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