在COVID-19期间的急性神经精神症状:来自两个独立的队列研究的结果
Daphne Everaerd, Pim Vissers1, Marloes van Helvoort1
1Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.
The Journal of nervous and mental disease
|August 9, 2023
概括
COVID-19影响中枢神经系统 (CNS),导致神经精神症状 (NPS),如焦虑和妄想. NPS与更高的重症监护病房 (ICU) 入院相关,但没有改变疾病严重程度或死亡率.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- COVID-19会影响多个器官系统,包括中枢神经系统 (CNS).
- 急性神经精神症状 (NPS) 在COVID-19患者中越来越多地被识别出来.
- 在COVID-19中最常见的特定NPS及其与疾病过程的关联仍然不清楚.
研究的目的:
- 为了确定COVID-19患者中最常见的急性NPS.
- 为了确定NPS是否与COVID-19严重程度,ICU入院或死亡率有关.
- 调查NPS和COVID-19的临床结果之间的关系.
主要方法:
- 这是一项回顾性队列研究,利用来自两个独立的学术医院队列的数据.
- 包括93名NPS患者和125名没有NPS的患者.
- 评估NPS类型,COVID-19严重程度 (CT分数),ICU入院和死亡率.
主要成果:
- Delirium,焦虑和情绪症状是观察到的最常见的急性NPS.
- 与没有NPS的患者相比,患有NPS的患者入院ICU的可能性更高.
- 两组之间在ICU停留时间,CT严重性得分或死亡率方面没有发现显著差异.
结论:
- 妄想,焦虑和情绪症状是COVID-19中普遍存在的NPS.
- 在COVID-19患者的ICU入院中,NPS是独立相关的.
- 建议对所有COVID-19患者进行NPS的积极查,特别是在ICU设置中.
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