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Updated: Jul 19, 2025

Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages
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卡斯帕酶-4二元化和D289自处理引发了一种介素-1β转化酶

Amy H Chan1, Sabrina S Burgener1, Kassandra Vezyrgiannis2

  • 1Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, The University of Queensland, St Lucia, Australia.

Life science alliance
|August 9, 2023
PubMed
概括

非正规的炎症酶使用caspase-4来防御细菌. 卡斯巴酶-4的激活和自我分裂导致细胞死亡和直接IL-1β成熟,独立于NLRP3炎症体.

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