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Updated: Jul 19, 2025

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退化的tRNA身份代码的结构基础以及人类线粒体tRNA识别中的双模特性的演变

Bernhard Kuhle1,2, Marscha Hirschi3, Lili K Doerfel3

  • 1Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA. bkuhle@scripps.edu.

Nature communications
|August 9, 2023
PubMed
概括

线粒体tRNAs在突变压力下演变,但人类线粒体seryl-tRNA合成酶识别了两个不同的tRNAs. 这种酶使用双模读出机制,展示了分子识别中的进化创新.

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