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Updated: Jul 19, 2025

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对CXCR4-CXCR7系统内在传感器合偏差的分子洞察

Parishmita Sarma1, Carlo Marion C Carino2, Deeksha Seetharama1

  • 1Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

Nature communications
|August 9, 2023
PubMed
概括

化基因受体CXCR4和CXCR7表现出不同的信号通路. CXCR7缺乏G蛋白合,但招募β-arrestin,而CXCR4激活G蛋白,但显示较少的β-arrestin合,影响免疫反应和药物发现.

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Transduction01:16

Transduction

Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
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