用FLT3抑制剂作为MRD引导的救援治疗,用于FLT3突变AML中的分子衰竭

Jad Othman1,2,3, Nicola Potter1, Katya Mokretar4

  • 1Department of Medical and Molecular Genetics, King's College London, London, England, UK.

Leukemia
|August 9, 2023
PubMed
概括

FLT3 抑制剂 (FLT3i) 显示为治疗 FLT3 突变的 AML 患者,在初始治疗后出现分子衰竭. 这种干预导致了分子反应和改善的生存率,这表明了预防复发的可行策略.

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