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Updated: Jul 19, 2025

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在β链受体接口上对菌体显示的Interleukin-2进行分子重塑,以获得具有更好的发育性概况的强效超级激动剂

Gertrudis Rojas1, Ernesto Relova-Hernández2, Annia Pérez-Riverón2

  • 1Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba. grojas@cim.sld.cu.

Communications biology
|August 9, 2023
PubMed
概括

经过工程改造的干白素-2 (IL-2) 变体显示对IL-2受体β链的结合增强,改善治疗潜力. 与现有版本相比,这些新型超级结合剂显示出更高的可开发性和体内疗效.

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