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美国成年人骨矿物质密度和肉症之间的相关性:基于人口的研究
Lulu Cheng1,2, Siyu Wang3
1College of Acupuncture-Moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, 230012, China. Chenglulu958@163.com.
Journal of orthopaedic surgery and research
|August 9, 2023
概括
腰椎骨矿物质密度 (BMD) 与美国成年人肉症有负面关联. 保持健康的肌肉-骨-脂质平衡可能有助于预防骨损失和肌肉消耗.
科学领域:
- 老年学是一门学科.
- 骨和矿物质的新陈代谢
- 营养科学 营养科学
背景情况:
- 衰老与身体组成的变化有关,包括骨质损失,这表明肌肉,骨和脂质新陈代谢之间存在联系.
- 了解这些组成部分之间的相互作用对于解决与年龄相关的健康问题至关重要.
研究的目的:
- 为了研究腰部骨矿物质密度 (BMD) 和肉症之间的关系.
- 在"肌肉-骨-脂质"框架内探索这种关联.
主要方法:
- 对来自8386名参与者 (20-59岁) 的NHANES 2011-2018数据进行横截面分析.
- 用DXA测量的腰部BMD和尾骨肌肉 (ASM);用BMI调整的ASM定义的麻症.
- 权重多变量和逻辑回归分析,包括合适的光滑曲线和值效应分析.
主要成果:
- 在腰部骨质疏松症和肉症之间发现了显著的负面关联.
- 腰部 BMD 的增加与肉症的风险大大降低有关 (OR=0.07 每单位增加).
- 保护性关联在BMI≥25的女性中更为强烈.
结论:
- 在美国成年人中,腰椎骨髓瘤与肉症相反相关.
- 这些发现突显了"肌肉-骨脂"动态在骨损失病原体中的重要性.
- 对这种相互作用的进一步研究可能会为预防与年龄相关的骨和肌肉衰退的策略提供信息.
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