在女性中与肥胖相关的性质下垂症
Pei Chia Eng1,2, Maria Phylactou1,3, Ambreen Qayum1,3
1Section of Endocrinology and Investigative Medicine, Imperial College London, London W12 0NN, UK.
Endocrine reviews
|August 10, 2023
概括
肥胖可能会导致女性的双胞胎缺血症,类似于男性的肥胖相关的二次双胞胎缺血症 (MOSH). 本综述探讨了独立于PCOS的潜在"女性肥胖相关的二次性阴性腺瘤" (FOSH) 的证据.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 肥胖医学 肥胖医学
背景情况:
- 男人肥胖相关的二次性性阴性腺体缺陷症 (MOSH) 是明确的.
- 多囊性卵巢综合征 (PCOS) 患病率随着肥胖增加,但通常涉及增加,而不是降低,淋巴腺激素水平.
- 肥胖会降低白化激素 (LH) 水平和女性的脉冲幅度,有或没有PCOS,这表明潜在的女性相当于MOSH.
结论:
- 肥胖可能会通过与PCOS不同的机制诱导女性的二次性阴性腺体缺陷症.
- 需要进一步的研究和表型化,以建立和调查FOSH.
- 了解FOSH可能会为肥胖女性带来新的诊断和治疗策略.
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