粘弹性测试:对新方法和当前文献的批判性评估
Geoffrey D Wool1, Timothy Carll1
1Department of Pathology, University of Chicago, Chicago, Illinois, USA.
International journal of laboratory hematology
|August 10, 2023
概括
新的粘弹性测试 (VET) 方法提供便携式,实时的凝块分析. 在不伤害患者的情况下,VET引导的输血可能会减少血液的使用,尽管需要更多的研究.
科学领域:
- 血液静止和血栓形成研究.
- 护理点诊断的诊断 护理点诊断
- 临床实验室科学 临床实验室科学
背景情况:
- 粘弹性测试 (VET) 随着新型卡特里奇测试方法的显著发展.
- 波共振是现代职业教育中用于凝块检测的关键技术.
- 基于卡的职业教育提高了可移植性,易用性,并在各种环境中提高了结果的稳定性.
研究的目的:
- 审查美国食品和药物管理局 (FDA) 批准的粘弹性测试 (VET) 方法的不断变化的格局.
- 检查VET在各种临床场景中的应用,包括手术,创伤和重症监护.
- 评估当前的证据和新一代职业教育工具的未来方向.
主要方法:
- 目前美国食品和药物管理局 (FDA) 批准的粘弹性测试 (VET) 方法的审查.
- 分析各种临床环境中的职业教育应用,如心脏手术,创伤,肝移植,产科和COVID-19.
- 对新一代职业教育仪器 (TEG 6s,HemoSonics Quantra,ROTEM sigma) 的证据评估.
主要成果:
- 与传统方法相比,卡式职业教育提供了更好的易用性,便携性和稳定性.
- 职业教育和培训应用于各种临床情况,包括高风险手术和特定患者群体.
- 目前对于新一代职业教育设备的高质量随机试验证据有限.
结论:
- 通过VET指导的输血算法在减少血液产品的利用率方面显示出有前途,而不会影响患者的治疗结果.
- 进一步的研究,包括对新的职业教育工具的比较试验和临床切线的验证,是必不可少的.
- 通过职业教育和培训 (VET) 进行治疗点凝血监测的进展可以改善流血患者的输血管理.
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