在低侵袭性牙科手术中管理全身麻醉,同时保持低度雷米芬坦尼尔的自发呼吸:一个横截面研究
Daijiro Ogumi1, Shota Abe1, Hikaru Sato1
1Department of Dental Anesthesiology, Ohu University, School of Dentistry, Fukushima, Japan.
Journal of dental anesthesia and pain medicine
|August 10, 2023
概括
这项研究发现,随着患者年龄的增长,在全身麻醉和自发呼吸期间,所需的雷米芬坦尼尔剂量下降. 这种低剂量雷米芬坦尼尔和塞沃弗兰的技术在牙科手术中是安全有效的.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 评估了患者年龄和雷米芬坦尼尔剂量速率之间的关系.
- 在sevoflurane中使用低剂量的remifentanil用于自发呼吸的全身麻醉.
- 专注于美国麻醉师协会身体状况为1或2的患者.
研究的目的:
- 为了确定患者年龄和雷米芬坦尼尔输液率之间的相关性.
- 建立适合年龄的雷米芬坦尼尔剂量策略,用于自发呼吸麻醉.
- 评估这种麻醉技术在牙科手术中的安全性和有效性.
主要方法:
- 调整为减半自发呼吸速率的雷米芬坦尼尔输液速率.
- 在稳定条件下 (≥15分钟) 定义的雷米芬坦尼尔输液速率 (γH).
- 使用斯皮尔曼相关性分析了 γH 和患者年龄之间的关系.
主要成果:
- 在remifentanil剂量 (γH) 和患者年龄之间发现了显著的负相关性.
- 剂量率随着年龄的增加而下降,回归线y = -0.00079 x + 0.066.
- 雷米芬坦尼尔的剂量约为0.88毫升/小时 (0.1毫克/毫升稀释),保持稳定的EtCO2和SpO2,没有手术内事件.
结论:
- 使用低剂量雷米芬坦尼尔进行自发呼吸的全身麻醉在微创手术中是有效的.
- 已建立的年龄取决于剂量策略可确保安全和稳定的麻醉.
- 这种方法适用于需要在麻醉下自发呼吸的牙科治疗.
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