视网膜血管密度变化在患有大动脉回的患者中
Caner Topaloglu1, Sinan Bilgin2
1Department of Cardiology, Izmir University of Economics, Izmir, Turkey.
Cardiology research
|August 10, 2023
概括
患有大动脉反 (AR) 的患者表现出多层视网膜血管密度降低,包括表面毛细血管,深毛细血管和胆管毛细血管. 光学连贯断层扫描血管学 (OCTA) 揭示了这些微血管变化.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 医疗成像医学成像
背景情况:
- 大动脉反 (AR) 是一种影响血液流动的心血管疾病.
- 视网膜的微血管变化可能与AR等系统性疾病有关.
- 光学连贯断层扫描血管造影 (OCTA) 是用于视网膜血管的非侵入性成像技术.
研究的目的:
- 为了评估视网膜血管密度在表面毛细血管层,深毛细血管层,和choriocapillaris层.
- 为了比较AR患者和健康对照者之间的视网膜血管密度.
- 研究OCTA在评估AR微 perfusion中的潜力.
主要方法:
- 研究包括38名健康参与者和38名AR患者.
- 使用跨胸腔心声学 (TTE) 和AHA/ACC指南评估AR诊断和严重程度.
- 使用OCTA分析的视网膜血管密度 (SCPD,DCPD,CCPD).
主要成果:
- 在AR患者的鼻腔,下部和中部区域观察到表面毛细管密度 (SCPD) 的降低.
- 在AR患者的鼻腔和下部区域观察到较低的深层毛细血管密度 (DCPD).
- 在下部和中部区域发现较低的胆囊状质密度 (CCPD),与对照组相比,下部区域显著减少. 中部黄斑厚度也减少了.
结论:
- 与健康个体相比,AR患者的视网膜流动密度显著下降.
- OCTA可以有效地测量AR患者视网膜中的微 perfusion 变化.
- 视网膜微血管变化可能作为AR系统变化的指标.
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