评估头癌患者的风险因素:一个病例对照研究
Zohreh Dalirsani1,2, Zahra Delavarian1,2, Atessa Pakfetrat1,2
1Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Addiction & health
|August 10, 2023
概括
识别头部和部状细胞癌 (HNSCC) 的危险因素对于预防至关重要. 这项研究发现HNSCC与烟草吸烟,烟水使用,片消费和酒精之间存在显著的关联,患者的BMI和教育水平较低.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 头部和部状细胞癌 (HNSCC) 是全球流行的一种癌症.
- 识别风险因素对于有效的癌症预防策略至关重要.
- 这项研究的重点是确定伊朗马什哈德的HNSCC风险因素.
研究的目的:
- 调查和确定与头部和部状细胞癌 (HNSCC) 相关的关键风险因素.
- 为了比较HNSCC患者和健康的对照组之间各种风险因素的患病率.
- 为研究区域的向癌症预防计划提供数据.
主要方法:
- 采用了一种病例控制研究设计.
- 招募了76名HNSCC患者 (病例) 和91名健康人 (对照).
- 使用检查清单收集风险因素数据,并进行统计分析 (Chi-square,t-test,Mann-Whitney) 来比较群体并确定赔率比率.
主要成果:
- 与对照组相比,HNSCC患者的教育水平和体重指数 (BMI) 显着较低 (P<0.001).
- 在HNSCC和烟草吸烟 (每天和持续时间的香烟),水烟吸烟持续时间,每日片消费和酒精使用 (P值在0.001到0.05之间) 之间发现了显著的关联.
结论:
- 在HNSCC和增加的香烟吸烟,水使用,片消费和酒精摄入量之间存在直接关系.
- 较低的教育程度和BMI也与HNSCC有关.
- 建议进行进一步的大规模研究,以验证这些发现并将结果概括.
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