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德克萨米他静脉内置植入物用于斑点和一些其他罕见的表征在膜炎
Seher Koksaldi1, Mustafa Kayabaşi1, Zıya Ayhan1
1Department of Ophthalmology, Dokuz Eylul University, 35330 Izmir, Turkey.
Medicine international
|August 10, 2023
概括
室内甲松植入物 (IDI) 有效地治疗了乌维性斑点,改善视力和减少视网膜厚度. 虽然在非传染性紫外炎中通常是安全的,但建议在传染病例和特定并发症中谨慎使用.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 管道炎管理 管道炎管理
背景情况:
- 紫外线炎,特别是紫外线性黄斑,对视力构成重大威胁.
- 腹腔内皮质类固醇植入物为后段炎症提供持续药物输送选择.
- 在多样化的卵巢炎患者群体中评估静脉内甲素植入物 (IDI) 的疗效和安全性至关重要.
研究的目的:
- 在患有紫外线炎的患者中评估静脉内德克萨米他植入物 (IDI) 的结果.
- 为了评估IDI后视力敏度和中央黄斑厚度 (CMT) 的变化.
- 为了识别潜在的并发症和IDI在紫外线炎中的使用的具体指示.
主要方法:
- 从81名用IDI治疗的卵膜炎患者的110只眼睛进行了回顾性分析.
- 最短6个月的随访,数据收集在2012年1月至2022年9月之间.
- 在治疗前和治疗后评估最佳校正视敏度 (BCVA) 和中央黄斑厚度 (CMT).
主要成果:
- 显著改善BCVA (0.69至0.60 logMAR,P=0.008) 和减少CMT (499.74至296.60微米). 在BCVA (0.69至0.60 logMAR,P=0.008) 和减少CMT (499.74至296.60微米).
- IDI主要用于非传染性乌维性黄斑胀 (95.1%),但也用于特定的传染病例和预防.
- 常见的副作用:眼内压升高 (25.5%),需要局部治疗;罕见的并发症包括视网膜脱落和内.
结论:
- 室内甲松植入物 (IDI) 是一种有效的治疗乌维性黄斑,改善视力敏度和减少视网膜厚度.
- IDI证明了超出非传染性紫外线炎的实用性,包括系统性治疗不耐受症和术后斑点的预防.
- 虽然一般耐受性很好,但在膜炎的IDI治疗期间,仔细监测眼内压升高和其他罕见并发症是必不可少的.
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