东北医疗大脑磁共振成像研究:理由,设计和背景
Makiko Taira1,2,3, Shunji Mugikura1,2,3, Naoko Mori1,2,3
1Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
JMA journal
|August 10, 2023
概括
在TMM大脑MRI研究中,在大东日本地震后,从超过12,000名参与者收集了神经成像和神经心理数据. 这种全面的数据库有助于研究认知功能和心理健康.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 大东日本地震 (GEJE) 和海影响了居民的认知功能和心理健康.
- 针对心理健康和认知功能的个性化医疗保健需要强大的数据.
研究的目的:
- 建立一个全面的神经成像和神经心理数据数据库.
- 评估GEJE受影响居民的认知功能和心理健康.
- 为认知和心理健康推进个性化医疗.
主要方法:
- 从2014年7月开始,招募了12164名参与者参加基线调查.
- 收集的多模体MRI数据 (T1加权,MRA,DTI,pCASL,FLAIR). 这些数据包括:
- 评估神经心理状态使用验证的尺度 (基于问卷和采访).
主要成果:
- 建立了一个大型数据库,集成神经成像,心理和认知数据.
- 从TMM社区基队列研究和TMM出生和三代队列研究的参与者收集的数据.
- 目前正在进行的第二次调查于2019年10月启动.
结论:
- TMM大脑MRI研究为了解认知障碍和心理健康创造了宝贵的资源.
- 结合现有的TMM生物库基因组和奥米克数据,该数据库可以揭示病理和神经心理障碍之间的联系.
关键词:
TMM出生和三代队列研究 (TMM BirThree队列研究)TMM 基于社区的队列研究 (TMM Comm 队列研究)东北医疗大银行大脑磁共振成像研究 (TMM大脑MRI研究)认知障碍是一种认知障碍.神经成像是一种神经成像.神经心理评估 神经心理评估更多相关视频
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