脑卒中中门脱落:危险因素和左心房功能在密码性与非密码性缺血性亚型中的风险因素
Francesca Calicchio1,2, Lisa J Lim2, Danielle Cross3
1Department of Medicine (Cardiovascular Division), The Lundquist Institute at Harbor-University of California-Los Angeles Medical Center, Torrance, CA, United States.
Frontiers in neurology
|August 10, 2023
概括
脑卒中中门脱落 (MVP) 表明非密码性脑卒中与常见的危险因素有关,而不是传单厚度. 在MVP中密码性中风的原因需要进一步调查.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 密特拉脱落 (MVP) 与缺血性中风风险增加有关.
- 传统的风险因素包括年龄较大,叶片厚度,以及引起心房动的 mitra regurgitation (MR).
- 对于MVP中风亚型的具体风险因素尚不清楚.
研究的目的:
- 评估MVP患者的临床和心声学参数,以加密性 (C) 与非加密性 (NC) 卒中进行对比.
- 评估不同类型中风的MVP患者的左心房 (LA) 功能.
- 确定在MVP中区分C冲击和NC冲击的特定风险因素.
主要方法:
- 病例控制匹配研究分析了MVP患者中风后的心声图.
- 对MVP的定义:传单位移≥2mm.
- 分析LA和左心室 (LV) 功能,MR程度和小册子厚度.
主要成果:
- 30名中风MVP患者 (11名C型中风,19名NC型中风) 与20名没有中风的MVP患者和16名对照患者进行了比较.
- 没有中风的MVP与中风的MVP相比,BMI较低,高血压较低,但MR更多,LA功能异常.
- 在MVP中NC中风与更高的BMI,高血压和心房动有关;C中风患者与对照没有显著差异.
结论:
- 与MVP相关的MR可以提供对中风的保护,即使LA功能受损.
- 在MVP中,非密码性中风风险与常见的中风风险因素有关,而不是中枢单片厚度.
- 在MVP中密码性中风的潜在原因需要进一步的研究.
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