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nsP1中的G285S突变足以使Sindbis病毒成为基因传递的稳定载体

Xiangwei Shi1,2,3,4, Kangyixin Sun2,3,5, You Hu2,3

  • 1State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.

Frontiers in microbiology
|August 10, 2023
PubMed
概括

研究人员通过识别适应性突变来增强Sindbis病毒 (SINV) 基因传递. nsP1中的特定突变 (G285S) 稳定了转基因表达,改善了神经科学和瘤治疗的病毒载体能力.

关键词:
辛德比斯病毒 辛德比斯病毒适应性突变是一种适应性突变.指导进化是指导进化的.基因传递 基因传递 基因传递神经电路的神经电路.稳定的向量是稳定的向量.

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