多发性硬化 (MS) 和非MS患者的特征,并发症和并发症,为变形进行腰部融合
Aron Sulovari1, Etka Kurucan2, David Nathan Bernstein3
1Department of Anesthesiology, Westchester Medical Center, Valhalla, United States.
Surgical neurology international
|August 10, 2023
概括
经过脊髓融合治疗的多发性硬化症 (MS) 患者年轻,女性多,抑郁率更高. 然而,与非MS患者相比,MS患者的死亡率和并发症率相似.
科学领域:
- 脊柱外科手术 脊柱外科手术
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 脊柱形是一种复杂的疾病,需要进行手术.
- 多发性硬化症 (MS) 是一种慢性神经疾病,可能会影响手术的结果.
- 了解脊柱形患者和无脊柱形患者手术结果的差异对于患者护理至关重要.
研究的目的:
- 为了比较脊柱形患者的特征,并发症和并发症,多发性硬化症 (MS) 和没有多发性硬化症 (MS) 的患者接受初级腰椎融合.
- 为了确定患者的人口统计和与MS相关的临床因素在这个手术群体.
- 评估MS对手术结果的影响,包括死亡率和术后并发症.
主要方法:
- 从2003年到2014年使用全国住院患者样本 (NIS) 数据库.
- 用国际疾病分类第九次修订,临床修改代码,鉴定了为脊椎形进行初级腰椎融合的患者队列,有或没有MS,使用国际疾病分类第九版临床修改代码.
- 分析患者的特征,并发症和并发症,使用单变量和双变量统计方法.
主要成果:
- 患有多发性硬化症的患者年轻,女性更频繁,更有可能在城市教学医院接受手术.
- 与非MS患者相比,MS患者的抑郁率较高,但糖尿病,高血压和功能衰竭率较低.
- 在MS和非MS组之间没有观察到死亡率或整体外科手术后并发症率的显著差异.
结论:
- 脊椎形患者与MS经历初级腰部融合,具有不同的人口和并发症概况.
- 尽管存在这些差异,但在这种手术背景下,MS似乎不会显著增加死亡率或术后并发症风险.
- 这些发现强调了在治疗脊柱形时考虑患者特异性因素的重要性,包括MS等神经疾病.
相关概念视频
01:19Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
01:27Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
01:23Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...