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Updated: Jul 19, 2025

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
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在B细胞淋巴瘤瘤中,BCL3重组发生在与不同疾病相关的两个突破点群中

Anna Carbo-Meix1, Francesca Guijarro2, Luojun Wang3

  • 1Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona.

Haematologica
|August 10, 2023
PubMed
概括

BCL3重组 (BCL3-R) 会产生两个不同的淋巴瘤瘤. 上游断点模仿非典型的慢性淋巴细胞白血病,而下游断点类似于边缘区域淋巴瘤,在基因表达和表观遗传学上有所不同.

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