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Updated: Jul 19, 2025

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在Prox1上的禁食敏感SUMO开关控制肝脏胆固醇代谢.

Ana Jimena Alfaro1,2,3, Claudia Dittner4, Janina Becker4

  • 1Institute for Diabetes and Cancer, Helmholtz Munich, Neuherberg, Germany.

EMBO reports
|August 10, 2023
PubMed
概括

SUMOylation of Prox1,一个关键的转录因子,调节肝脏的禁食新陈代谢. 肥胖症中的SUMOylation受损破坏了这一点,但针对Prox1 SUMOylation可能会提供新的代谢健康策略.

关键词:
胆汁酸 胆汁酸是一种胆固醇 胆固醇 胆固醇肝脏 肝脏 肝脏 肝脏在Prox1中使用Prox1.这就是SUMOylation的作用.

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