在韩国一所大学医院爆发的人类甲型肺炎病毒的最新变化
Clinical laboratory
|August 10, 2023
概括
COVID-19大流行改变了人类甲型肺炎病毒 (HMPV) 爆发,季节性分布发生了显著的转变. 临床医生应对病毒流行病学模式的变化保持警.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- "COVID-19"大流行严重影响了呼吸道病毒的循环.
- 尽管由于隔离措施导致总体病毒检测率降低,但仍观察到某些病毒的意外流行,包括人类甲型肺炎病毒 (HMPV).
- 疫情前的HMPV爆发模式似乎在疫情期间发生了变化.
研究的目的:
- 在COVID-19大流行期间调查人类甲型肺炎病毒 (HMPV) 爆发的发病率和改变的分布模式.
- 为临床实践提供有关HMPV流行病学的宝贵见解.
- 为了确定HMPV季节性和共感染率的变化.
主要方法:
- 一项回顾性研究分析了2020年3月至2022年12月的HMPV发病率和分布.
- 多重聚合酶链反应 (PCR) 使用商业套件和FilmArray测定被用于呼吸道微生物检测.
主要成果:
- 2020年3月至2022年6月期间没有检测到HMPV,但在2022年7月出现,在9月至10月检测的峰值.
- 大多数HMPV病例 (92.5%) 发生在秋季,这表明与大流行前的季节性模式有所转变.
- 在3-6岁的儿童中,HMPV最常被检测到,并且经常与其他呼吸道病原体 (如鼻病毒和肠病毒) 一起发生.
结论:
- COVID-19 流行病明显改变了 HMPV 的季节性分布.
- 在HMPV流行病学的变化表明其他呼吸道病毒模式的潜在转变.
- 医疗保健提供者必须意识到这些不断变化的病毒流行病学趋势,并保持临床警.
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