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Updated: Jun 28, 2026

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
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利用心肌细胞生产的发育线索

Renee G C Maas1, Floor W van den Dolder2, Qianliang Yuan2

  • 1Utrecht Regenerative Medicine Center, Circulatory Health Laboratory, University Utrecht, Experimental Cardiology Laboratory, Department of Cardiology, University Medical Center Utrecht, 3508 GA Utrecht, the Netherlands.

Development (Cambridge, England)
|August 10, 2023
PubMed
概括

了解Wnt和Hippo等心脏生长信号是关键. 需要新的策略来刺激成人心脏的心脏再生和心肌细胞更新.

关键词:
心肌细胞的生产.心肌细胞的增殖和扩散心肌细胞自我更新胚胎生长途径 胚胎生长途径胎儿基因程序 胎儿基因程序心脏的再生心脏的再生河马的信号传递没有信号发送.这就是hiPSC-CM.

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相关概念视频

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...