对临床适应性放射治疗用于头癌的系统性审查
Anne Marie Lindegaard1, Katrin Håkansson1, Mogens Bernsdorf1
1Department of Oncology, Centre for Cancer and Organ diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Acta oncologica (Stockholm, Sweden)
|August 10, 2023
概括
适应性辐射疗法 (ART) 治疗头癌 (HNC) 显示,对有风险的器官的剂量减少很小. 然而,它对毒性和疾病控制等临床结果的影响仍然不确定,需要进一步研究.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 在瘤学瘤学.
背景情况:
- 头癌 (HNC) 患者在放射治疗 (RT) 期间经历了解剖学变化,可能会损害治疗的准确性.
- 适应性放射疗法 (ART) 旨在解决这些变化,但涉及大量的工作负担.
- 本综述使用前性数据评估了HNC中ART的临床和剂量学益处.
结论:
- 目前关于ART在HNC的临床益处的证据有限.
- 虽然ART提供了微小的剂量测量优势,但其对患者毒性和长期疾病控制的最终影响需要进一步研究.
- 需要使用强大的对照组进行更大规模的前性试验,以澄清ART在HNC治疗中的作用.
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