相关实验视频
Updated: Jun 23, 2026

13:21
Graphene Coatings for Biomedical Implants
Published on: March 1, 2013
21.3K
用正电荷增强表面:新开发的阴离子涂层结合了对植入物应用的抗腐蚀和杀菌特性
João Pedro Dos S Silva1, Raphael C Costa1, Bruna E Nagay1
1Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas (UNICAMP), Av. Limeira, 901, Piracicaba, São Paulo 13414-903, Brazil.
ACS biomaterials science & engineering
|August 10, 2023
概括
血电解氧化 (PEO) 预处理增强了 (Ti) 表面,改善了骨质整合和耐腐蚀性. 这种新的方法创造了杀菌性阴阳性涂层,降低了植入物失败的风险.
科学领域:
- 生物材料科学 生物材料科学
- 表面工程是什么?表面工程是什么?
- 牙科植入物学 牙科植入物学
背景情况:
- 牙周植入物疾病和骨整合不良是导致牙科植入物失败的主要原因.
- 生物膜积累和腐蚀性金属离子有助于植入物失败.
- 阴离子涂层显示出杀死病原体和耐腐蚀的潜力,但缺乏有利于骨质整合的地形.
研究的目的:
- 为了研究血电解氧化 (PEO) 作为 (Ti) 表面的预处理.
- 开发具有改善骨质整合性质的杀菌性和耐腐蚀性阴离子涂层.
- 为了比较PEO预处理与Ti表面修饰的传统热水处理 (HT).
主要方法:
- (Ti) 表面使用PEO或HT进行预处理,以引入基 (-OH) 基.
- 使用3-aminopropyltriethoxysilane (APTES) 进行了化,以创建阴离子涂层.
- 表面特征包括里埃变换红外光谱学,X射线光电子光谱学,以及机械,三角学,腐蚀和生物性质的评估.
主要成果:
- 与HT和未经处理的Ti相比,PEO创造了一个多孔的Ti表面,其粗度增加,机械和 Tribological 性能优越.
- PEO和HT都增加了表面可湿性,由-OH组的引入证实;化导致了具有氨基功能组的疏水表面.
- PEO+APTES组表现出增强的耐腐蚀性,并有效杀死*黄金菌*和*大肠杆菌*,具有非细胞毒性和类似Ti的蛋白质吸附性.
结论:
- 氧化是一种对Ti表面的有前途的预处理方法,可产生可裁剪的多孔氧化物涂层.
- 基于PEO的阴阳性涂层显示出增强抗菌性和耐腐蚀性能的潜力.
- 这种方法为开发下一代牙科和生物医学植入物提供了途径,改善了骨质整合和降低了失败率.
相关概念视频
Colloidal precipitates
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Microbial Corrosion
Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...

