在COVID-19后的全球背景下,重新定义低收入和中等收入国家的癌症研究重点:修改后的德尔菲共识进程
Louis Fox1, Aida Santaolalla1, Jasmine Handford1
1Translational Oncology and Urology Research (TOUR), Centre for Cancer, Society and Public Health, King's College London, London, United Kingdom.
JCO global oncology
|August 10, 2023
概括
资源较少的地区的癌症研究重点集中在调整治疗方法,改进注册表和预防上. 结果指导未来的癌症研究资金和战略在资源挑战的设置.
科学领域:
- 全球健康 全球健康
- 在瘤学瘤学.
- 卫生系统研究 卫生系统研究
背景情况:
- 在COVID-19后,为癌症研究提供资金是具有挑战性的,特别是在资源有限的地区 (RCRs).
- 在RCRs中有限的研究生态系统需要有针对性的研究优先级.
- 确定优先事项需要来自研究人员和患者的投入.
研究的目的:
- 为资源有限的国家建立癌症研究领域的优先清单.
- 在低收入和中等收入国家为战略癌症研究投资提供信息.
- 在RCR中,使研究工作与患者和医疗保健系统的需求保持一致.
主要方法:
- 对来自低收入和中等收入国家的151名癌症专家进行了修改后的Delphi调查.
- 两轮调查评估了预先确定和建议的研究优先事项的重要性.
- 强制选择排名和复合投票分数 (T分数) 确定了最终的优先级列表.
主要成果:
- 首要任务是使治疗指南和策略与可用资源相适应 (T=83).
- 其他主要优先事项包括癌症登记 (T=62),预防 (T=52),终身护理 (T=53) 和负担得起的护理 (T=51).
- 对于COVID-19/癌症研究,重点包括大流行后维护战略 (T=36) 和大流行准备 (T=18).
结论:
- 在RCR中的战略癌症研究重点包括适应性治疗指南和可持续的注册表.
- 预防,以价值为基础的护理,研究能力建设和解决不平等问题至关重要.
- 研究应侧重于当地风险因素和公平获得护理和预防.
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