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Updated: Jul 19, 2025

Characterizing Mutational Load and Clonal Composition of Human Blood
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在患有固体瘤的患者中,癌症倾向突变和克隆性血液形成之间的关联

Sebastià Franch-Expósito1,2, Miika Mehine1,2, Ryan N Ptashkin2,3

  • 1Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.

JCO precision oncology
|August 10, 2023
PubMed
概括

基因损伤反应基因的遗传突变与固体瘤患者的克隆血液形成 (CH) 有关. 这种关联可能会增加二次白血病的风险,强调需要加强监测.

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