节律失常的米特拉脱落和米特拉环状断层:病理生理学,风险分层和管理
Benjamin Essayagh1,2, Avi Sabbag3, Edward El-Am1
1From the Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905, USA.
European heart journal
|August 10, 2023
概括
密特拉脱落 (MVP) 可能与危险的心律失常有关,挑战其良性感知. 研究突出了不律性MVP表型和对风险分层和管理的 mitra annular disjunction (MAD).
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 膜心脏疾病 膜心脏疾病
背景情况:
- 密特拉脱落 (MVP) 是常见的,但其心律失常形式 (AMVP) 和与突发心脏死亡的联系仍然存在争议.
- 在MVP中中环断节 (MAD) 的意义也很少被理解.
- 最近的数据挑战了MVP通常是良性的观念,揭示了与显著心室心律失常相关的表型.
研究的目的:
- 审查心律不整的米特拉脱落 (AMVP) 的定义,评估,随访和管理.
- 强调在AMVP表型中中环断节 (MAD) 的作用.
- 为高风险MVP患者提出风险分层途径.
主要方法:
- 审查最近的案例系列和队列研究.
- 临床,多模式成像和电生理学评估的分析.
- 综合专家共识声明和研究建议.
主要成果:
- MVP并不总是良性的;特定的表型与显著的心室节律失常有关.
- 节律失调的MVP (AMVP) 影响了高风险的MVP患者的一个子集.
- 中心环状断裂 (MAD) 是高风险AMVP表型的一个关键特征.
结论:
- 最近的研究完善了对不律性MVP表型和MAD的作用的理解.
- 提出的临床途径有助于风险分层,并指导MVP患者的管理决策.
- 需要进一步的研究,以充分阐明AMVP和MAD的机制和最佳治疗.
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