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预后和风险分层的轨迹对于患有骨髓质疏松综合征的患者

Amy E DeZern1, Peter L Greenberg2

  • 1Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

Blood
|August 10, 2023
PubMed
概括

骨髓质疏松症候群 (MDS) 的风险分层在过去的五十年中得到了发展. 目前的系统,包括分子国际预后评分系统,整合遗传数据,以改善患者管理.

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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