月经周期长度,2019年冠状病毒疾病 (COVID-19) 和疫苗接种之间的关联
Alexandra Alvergne1, Emily Boniface, Blair Darney
1Institute for Evolutionary Sciences, Montpellier University, Montpellier, France; the School of Anthropology and Museum Ethnography, University of Oxford, Oxford, United Kingdom; the Department of Obstetrics and Gynecology, Oregon Health & Science University, and the OHSU-PSU School of Public Health, Portland, Oregon; the National Institute of Public Health (INSP), Center for Population Health (CISP), Cuernavaca, Morelos, Mexico; and Clue by BioWink GmbH, Berlin, Germany.
经历COVID-19或接种COVID-19疫苗与轻微的月经周期长度变化有关. 这些对月经周期的临时影响在下一个月经周期之前就会消失.
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 月经周期的规律性是生殖健康的关键指标.
- 急性疾病和疫苗接种对月经周期的影响需要进一步研究.
研究的目的:
- 为了评估2019年冠状病毒病 (COVID-19) 和月经周期长度之间的关联.
- 为了将这些变化与接种COVID-19疫苗后的变化或在未接种疫苗的非患病的对照组中进行比较.
主要方法:
- 从周期追踪器应用程序中对前性跟踪的月经周期数据进行回顾性队列分析.
- 包括16至45岁定期月经周期的用户,分析COVID-19症状,疫苗接种或控制期的变化.
- 混合效应模型用于比较用户在事件前,事件期间和事件后的周期长度变化.
主要成果:
- 与事件前的周期相比,COVID-19感染与周期长度增加1.45天有关.
- 接种COVID-19疫苗与周期长度增加1.14天有关.
- 对照组显示周期长度减少0.68天;COVID-19和疫苗接种组的变化没有显著差异,并在下一个周期内得到解决.
结论:
- COVID-19感染与小,暂时的月经周期长度变化有关,与COVID-19疫苗接种后观察到的变化相似.
- 在COVID-19或疫苗接种后的月经周期变化是短暂的,在一个周期内得到解决.
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