损伤行为映射表明,关联记忆的状基质具有战略性作用
Shir Ben-Zvi Feldman1, Nachum Soroker2, Daniel A Levy3
1Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel; Baruch Ivcher School of Psychology, Reichman University, Herzliya, Israel.
概括
右侧角-角皮质,而不是腹角皮质,对于战略性情节性记忆回忆至关重要,特别是在跨模态任务中克服语义偏差.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 神经学 神经学
背景情况:
- 神经成像研究表明,腹壁皮质 (VPC),包括角圈,对情节性记忆至关重要.
- 以前的研究表明,VPC和侧面皮层病变会损害回忆力,特别是在跨模态关联方面.
- 这些地区的确切作用 - - 维护代表性与战略召回 - - 尚不清楚.
研究的目的:
- 区分腹壁皮质皮质和侧面皮质在维持关联表征与战略回忆中的作用.
- 调查VPC在情节性记忆任务中的语义处理中的参与.
- 澄清关联性识别的神经基础,特别是关于语义相关性的.
主要方法:
- 使用联想式识别任务与单模和跨模对.
- 操纵了备忘录的语义相关性,以评估偏见效应.
- 在62名亚急性中风患者和65名健康对照中采用了基于声素的病变行为映射 (VLBM).
主要成果:
- 卒中患者与无关联的重组对相比,表达了语义相关的虚假识别的增加.
- VLBM涉及到右侧的temporo-parietal区域的赤字与交叉模式对,特别是相关的,与语义偏差相关.
- 腹腔壁膜和侧面皮层损伤并没有影响不相关项目的记忆.
结论:
- 右侧角-角皮质在情节性关联记忆中发挥着战略作用,而不是代表性记忆.
- 这个区域的完整性对于在关联识别过程中克服语义干扰很重要.
- 研究结果表明,在temporo-parietal区域中,战略记忆和代表性记忆功能之间存在分离.
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