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Updated: Jul 19, 2025

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人化的小鼠肝脏显示了肝脏基本代谢功能的内皮控制

Eleanna Kaffe1, Manolis Roulis1, Jun Zhao2

  • 1Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.

Cell
|August 10, 2023
PubMed
概括

人类肝细胞 (肝细胞) 的功能由周围的非辅酶细胞 (NPC) 控制. 这项研究揭示了人类肝脏代谢和疾病的微环境调节,影响肝脏健康.

关键词:
FZD5 其他WNT2 其他胆酸结合胆固醇纤维化人性化肝脏血脂组学肝脏内皮细胞非酒精性脂肪肝疾病星状细胞

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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