直接阳光诱导的室温合成抗癌和催化银纳米颗粒由贝废弃物衍生的奇托桑
Gautham Devendrapandi1, Deepakrajasekar Padmanaban2, Rabi Thanikasalam3
1Department of Polymer Science, University of Madras, Chennai, Tamilnadu, India.
International journal of biological macromolecules
|August 10, 2023
概括
海洋废弃物酸盐 (CS) 用于制造具有抗癌和染料污染物去除特性的银纳米粒子 (Ag NPs-CS). 这种可持续的方法有效地管理生物废物,并为生物医学和环境应用产生功能性纳米材料.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 生物技术是生物技术.
背景情况:
- 海洋废物,特别是贝,是生物废物的重大挑战.
- 基托 (CS) 是从甲类中的基中提取的,是一种多功能生物聚合物,具有潜在的应用.
- 纳米材料合成为利用废品和开发新型功能材料提供了机会.
研究的目的:
- 使用海洋废物衍生的酸盐合成酸盐覆盖的银纳米粒子 (Ag NPs-CS).
- 研究Ag NPs-CS对人类肺腺癌细胞系的潜在抗癌特性 (A549).
- 评估Ag NPs-CS在降解混合染料污染物的有效性.
主要方法:
- 酸盐 (CS) 是通过去矿化,脱蛋白化和脱乙化从贝废物中提取的.
- 银纳米粒子 (Ag NPs) 通过光化学合成,使用CS作为直接阳光下的封闭剂.
- 对Ag NPs-CS的表征涉及UV-Vis光谱和FTIR分析.
- 对不同度的A549细胞系进行了抗癌活性评估.
- 染料降解效率使用甲蓝,罗达胺B和甲基色的混合溶液进行了测试.
主要成果:
- 通过特有的表面等离子体共振 (400 nm) 和FTIR峰值 (OH/NH2,CH, -CO) 证实了CS-AgNP的形成.
- Ag NPs-CS对A549细胞表现出显著的抗癌活性,细胞死亡在70μg/mL时达到52%.
- 水性Ag NPs-CS降解超过95%的混合染料溶液 (甲蓝,罗达胺B,甲基) 在100μg/mL下降解.
结论:
- 皮废弃物可以有效地用于合成素覆盖的银纳米粒子 (Ag NPs-CS).
- 合成的Ag NPs-CS表现出有希望的抗癌特性和强大的染料污染物降解能力.
- 这些发现强调了CS-Ag NP从海洋废物中获得的潜力,用于双重生物医学和环境应用.
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