自身免疫性多神经病变 自身免疫性多神经病变
Ryan Naum1, Kelly Graham Gwathmey2
1Department of Neurology, Virginia Commonwealth University, Richmond, VA, United States.
Handbook of clinical neurology
|August 10, 2023
概括
本章回顾了免疫媒介运动神经病变,不包括AIDP和CIDP. 这些自身免疫性疾病的早期诊断和治疗改善了患者的治疗结果.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 周围神经系统疾病 周围神经系统疾病
背景情况:
- 带有运动症状的自身免疫外围神经病变多样化,存在于各种临床环境中.
- 本综述侧重于免疫介导,运动主导的神经病变,不包括急性炎症性脱髓性多基基隆性神经病变 (AIDP) 和慢性炎症性脱髓性多基隆性神经病变 (CIDP).
研究的目的:
- 要突出常见的免疫介导,运动主导的神经病变.
- 讨论获得的脱髓化神经病变,根基复合神经病变以及与类风湿病相关的疾病.
- 强调早期识别和治疗对改善结果的重要性.
主要方法:
- 文献综述和综合有关免疫媒介运动神经病的当前知识.
- 神经病变的分类包括远端CIDP,多焦点运动神经病变,根基复合神经病变 (糖尿病和非糖尿病的腰部神经骨质根基复合神经病变,神经动脉缩/帕森奇-特纳综合征),以及与Sjögren综合征和类风湿性关节炎相关的神经病变.
主要成果:
- 识别和描述了AIDP和CIDP以外的关键免疫媒介运动神经病变.
- 详细介绍了诸如多焦点运动神经病变,根结复合神经病变以及与类风湿病相关的具体疾病.
- 强调了这些独特的神经病变的临床谱和诊断考虑因素.
结论:
- 早期识别运动占主导地位的自身免疫神经病变至关重要.
- 启动免疫调节和免疫抑制疗法可能会改善临床结果.
- 了解这种多样化的神经病变群体有助于及时有效的患者管理.
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