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Updated: Jul 19, 2025

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达拉图姆单一治疗耐火性狼性炎的治疗方法

Dario Roccatello1, Roberta Fenoglio2, Ilaria Caniggia2

  • 1University Center of Excellence on Nephrological, Rheumatological and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) including Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley (North-West Italy), San Giovanni Bosco Hub Hospital, ASL Città di Torino and Department of Clinical and Biological Sciences of the University of Turin, Turin, Italy. dario.roccatello@unito.it.

Nature medicine
|August 10, 2023
PubMed
概括

达拉图马布是一种抗CD38抗体,在治疗难治性狼性炎 (LN) 中表现有前途. 在6名患者中,有5名患者经历了12个月后疾病活性降低,蛋白尿和功能改善.

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Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
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