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Updated: Jul 19, 2025

RhoC GTPase Activation Assay
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B型plexins促进Ran的GTPase活性,以影响前列腺癌中的雄激素受体核转位

Ritu Garg1, Sofia Endzhievskaya2, Magali Williamson3

  • 1School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.

Cancer gene therapy
|August 10, 2023
PubMed
概括

B型素作为Ran的GTPase激活蛋白 (GAPs) 起作用,调节核运输. 这种机制解释了前列腺癌如何成为抗抗雄激素剥夺疗法的机制.

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