患有持续性动脉管的早产婴儿的营养:现有证据和实际影响
Chiara Lembo1, Afif El-Khuffash2, Christoph Fusch3,4
1Department of Neonatology, APHP, Necker-Enfants Malades Hospital, Paris, France.
早产婴儿的持续性动脉管 (PDA) 通常会导致胃肠道问题,使营养护理复杂化. 肠道营养通常被推给PDA婴儿,但需要更多的研究来确定最佳的养指南.
科学领域:
- 新生儿医学 新生儿医学
- 儿科胃肠病学 儿科胃肠病学
- 心脏病学 心脏病学
背景情况:
- 专利导管动脉 (PDA) 在早产婴儿中很普遍,发病率与妊娠年龄相反.
- PDA与严重的胃肠道并发症有关,包括食不耐受,穿孔和死性肠球炎,挑战营养管理.
- 这些并发症是实现充足营养摄入的主要障碍,可能会影响脆弱的早产儿的生长和长期健康.
研究的目的:
- 审查目前关于PDA早产婴儿营养管理的知识.
- 讨论PDA对这一群体的营养习惯的临床影响.
- 发现研究中的差距,并倡导制定基于证据的指导方针.
主要方法:
- 这是一个叙事综述,综合现有文献.
- 它涉及欧洲儿科研究学会营养,胃肠病学和新陈代谢和循环部分之间的合作.
- 该审查侧重于PDA,营养和早产婴儿护理的交集.
主要成果:
- 在肠道养过程中,PDA的存在不会显著损害介质体血流或体氧化.
- 在PDA婴儿中,流体限制可能导致营养摄入不足,从而对生长产生负面影响.
- 对于被诊断患有PDA的婴儿,建议启动或继续肠道营养.
结论:
- 在患有PDA的早产婴儿中,可以安全地开始或维持肠道营养.
- 进一步进行精心设计的研究至关重要,以便在PDA治疗之前,期间和之后制定明确的营养支持指南.
- 需要制定具体的指导方针,以优化肠道营养的实施,并为患有PDA的早产婴儿制定目标.
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