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Updated: Jul 19, 2025

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神经退行性疾病中的TMEM106B聚合:将遗传与功能联系起来

Hai-Shan Jiao1, Peng Yuan2, Jin-Tai Yu3

  • 1Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

Molecular neurodegeneration
|August 10, 2023
PubMed
概括

TMEM106B基因的突变与神经退行性疾病有关. 新的研究表明TMEM106B蛋白聚合,而不是功能丧失,破坏细胞过程并提供潜在的治疗点.

关键词:
聚合是一种聚合.粉样纤维素是粉样纤维素的组成部分.lysosome 是一种溶解体.神经退行发生神经退行.在TMEM106B中使用.治疗方法 治疗方法

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