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Updated: Jul 19, 2025

Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model
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诱导血红素酶-1通过调节HIF-1α来对抗PM2.5诱导的肺VEGFA表达

Huan Xu1,2, Qing Wen1, Xiuduan Xu1,2

  • 1Beijing Institute of Basic Medical Sciences, Beijing, People's Republic of China.

Journal of biochemical and molecular toxicology
|August 11, 2023
PubMed
概括

血氧酶-1 (HO-1) 通过减少血管内皮生长因子A (VEGFA) 的产生,保护免受颗粒物 (PM) 2.5诱导的肺损伤. 这种机制涉及抑制缺氧诱导因子1α (HIF-1α).

关键词:
这就是HIF-1α.这就是HO-1的HO-1.对于PM2.5来说,这是一个很好的例子.在VEGFA中,VEGFA是VEGFA.肺炎是一种肺炎.自己保护的自我保护.

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