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Updated: Jul 19, 2025

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
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Published on: May 22, 2019

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突变导致X链接氨基基基因不完善改变miRNA形成从氨基基基因exon4

R Shemirani1,2, M H Le2,3,4, Y Nakano1,5

  • 1Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, USA.

Journal of dental research
|August 11, 2023
PubMed
概括

原蛋白基因exon4和exon5中的突变破坏了exon4的拼接,影响了microRNA的产生,并导致X链接的原蛋白不完美. 这会影响牙面膜的形成和牙的发育.

关键词:
有关RNA拼接因素的RNA拼接因素替代性拼接是一种替代性的拼接.质细胞 (ameloblasts) 是一种细胞.艾梅洛基尼斯的诞生牙的牙质是指牙上的牙质.质的发育缺陷 质的发育缺陷

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