焦虑和抑郁的认知功能:来自ALSPAC队列的结果
Steph Suddell1,2,3, Liam Mahedy1,2,3, Caroline Skirrow1,4
1School of Psychological Science, University of Bristol, Bristol, UK.
Royal Society open science
|August 11, 2023
概括
焦虑和抑郁会影响情绪识别和工作记忆,但不会抑制反应. 需要进一步的研究来证实心理健康和认知功能之间的因果关系.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 遗传学 遗传学 是一个
背景情况:
- 焦虑和抑郁与认知障碍有关.
- 了解这些缺陷对于干预和预防功能衰退至关重要.
研究的目的:
- 研究焦虑,抑郁和认知领域 (情绪识别,反应抑制,工作记忆) 之间的关系.
- 使用观测和遗传方法检查横截面,前性和因果关系.
主要方法:
- 利用了来自阿文长度研究的父母和儿童 (ALSPAC) 的数据.
- 采用了对跨部门和潜在协会的观察分析.
- 应用孟德尔随机化 (MR) 来探索因果关系.
主要成果:
- 焦虑与幸福感识别减少和工作记忆较差有关.
- 抑郁症与增加悲伤的认知有关.
- 没有发现与抑制反应有显著的关联.
- 门德尔的随机化分析不足以确定因果关系.
结论:
- 结果表明,情绪识别和一些执行功能缺陷的中度变化,特别是工作记忆.
- 结果表明,对焦虑/抑郁和认知之间的因果关系的证据有限.
- 洞察力可以指导心理健康状况中的认知障碍的心理社会干预措施的发展.
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