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新的XEN63凝支架植入在开放角眼中:为期两年的随访试点研究
Bogomil Voykov1, Emil Nasyrov1, Jonas Neubauer1
1Centre for Ophthalmology, University Hospital Tuebingen, Tuebingen, Germany.
Clinical ophthalmology (Auckland, N.Z.)
|August 11, 2023
概括
修改后的XEN63凝支架显著降低了青光眼患者的眼内压力和药物使用. 这种有效的治疗显示了可管理的并发症,没有长期问题.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械 医疗器械
背景情况:
- 对于玻璃眼的过手术存在风险.
- 在XEN凝支架标准化水性幽默的外流.
- 最近推出了一个修改后的XEN63支架版本.
研究的目的:
- 评估修改后的XEN63凝支架的疗效和安全性.
- 评估对眼内压力 (IOP) 和药物需求的影响.
- 确定成功率和并发症率.
主要方法:
- 预期的,非随机的,观察的案例系列.
- 包括开角玻璃眼患者,尽管服用药物,但内脏压力高.
- 主要结局:中位IOP的变化;次要结局:药物改变,成功,针,并发症.
主要成果:
- 两年后,中位IOP从35.5mmHg降至11.5mmHg (p=0.03). 在两年后,中位IOP从35.5mmHg降至11.5mmHg (p=0.03). 在两年后,中位IOP从35.5mmHg降至11.5mmHg (p=0.03).
- 中位数的内血压降低药物从4.0降低到0 (p=0.03).
- 83%的人取得了完全的成功;33%需要注射;50%的人患有过渡性症状性低血压.
结论:
- 修改后的XEN63凝支架显著降低了IOP和药物负担.
- 并发症是可以管理的,并没有导致长期的后果.
- 这种设备提供了一种安全有效的替代品,用于治疗青光眼.
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