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合移植拒绝和冠状病毒疾病2019年感染:叙述性审查
Seyed Amirhossein Fazeli1, Amirhesam Alirezaei1, Amirhossein Miladipour1
1Department of Nephrology, Clinical Research and Development Center at Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Advanced biomedical research
|August 11, 2023
概括
冠状病毒疾病2019 (COVID-19) 流行病影响移植接受者. 这篇评论考察了COVID-19的情况.
科学领域:
- 腎病學和移植免疫學.
- 传染病与公共卫生问题
背景情况:
- 由于COVID-19的流行,全球健康和经济面临重大挑战.
- COVID-19是一种全身性疾病,可以影响多个器官,包括脏.
- 现有的研究记录了COVID-19对急性损伤和病患者的影响.
研究的目的:
- 审查有关患有COVID-19的脏移植接受者的当前研究.
- 在这些患者中分析脏异构移植排斥的发生率.
- 讨论免疫抑制管理,排斥风险因素和结果.
主要方法:
- 对当前文献进行系统审查.
- 对专注于被诊断患有COVID-19的移植接受者的研究进行分析.
- 检查有关异构移植排斥,免疫抑制,捐赠者特异性抗体和排斥史的数据.
主要成果:
- 报告显示,移植患者中存在各种COVID-19相关的脏疾病.
- 专注于脏异种移植排斥发生率和结果.
- 评估免疫抑制策略及其与排斥风险的关联.
结论:
- 对于接受脏移植的人来说,COVID-19带来了独特的挑战.
- 了解拒绝发生率,风险因素和结果对于患者管理至关重要.
- 需要进一步的研究来优化对这一脆弱群体的护理.
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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention
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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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