在患有骨质疏松症的患者中,化疗的有效性和安全性
V M Suslov1, L N Lieberman1, P G Carlier2
1Department of Rehabilitation, Federal State Budgetary Educational Institution of Higher Education Saint-Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation, Saint Petersburg, Russia.
Frontiers in neurology
|August 11, 2023
概括
定期游泳运动显著改善了杜申肌肉发育不良 (DMD) 的儿童的运动和功能测试. 这种水力康复计划被证明是有效和安全的,在四个月内没有对疾病活动产生负面影响.
科学领域:
- 儿科康复儿童康复中心
- 神经肌肉疾病 神经肌肉疾病
- 水上治疗水疗疗法
背景情况:
- 杜申肌肉发育不良 (DMD) 是一种渐进的儿童遗传疾病,导致早期残疾.
- 建议进行物理治疗,特别是水中运动,以控制DMD的进展.
- 游泳池运动提供平衡的肌肉参与,并促进呼吸练习.
研究的目的:
- 评估杜申肌力发育不良症儿童4个月定期游泳池炼计划的有效性.
- 评估能够独立运动的患者的功能改善.
- 为了确定水疗康复对肌肉结构的安全性和影响.
主要方法:
- 28名DMD患者 (年龄为6.9±0.2岁) 参加了为期4个月的水力康复计划.
- 评估包括6分钟的步行测试和定时功能测试 (上升,跑步,爬楼梯/下降).
- 使用定量肌肉MRI来监测肌肉结构和疾病活动 (肌肉水T2).
主要成果:
- 在6分钟步行测试 (462.7m至492.0m) 和所有计时功能测试 (p < 0.001) 中观察到统计学上显著的改善.
- 定时功能测试显示,在从地板上升,10米跑步和爬楼梯/下降方面表现更快.
- 肌肉水T2水平保持不变,表明对疾病活动没有不良影响.
结论:
- 定期在水中进行动态有氧运动对于改善DMD患者的功能移动性是有效的.
- 4个月的水疗康复计划证明了安全性,没有对DMD疾病活性产生负面影响.
- 水疗是一种有益的干预措施,用于患有杜氏肌肉发育不良的儿童.
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