一个巨大的甲状腺腺瘤呈现与甲状腺危机
Sara Esteves-Ferreira1, Leonor Rodrigues1, Rosa Dantas1
1Endocrinology Department, Centro Hospitalar do Baixo Vouga, Aveiro, PRT.
Cureus
|August 11, 2023
概括
巨型副甲状腺瘤 (GPA) 可以模仿副甲状腺癌 (PC),很少呈现为副甲状腺危机. 这个案例突出了GPA导致危及生命的高血危机,强调了诊断挑战.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 巨型副甲状腺瘤 (GPA) 是一种良性瘤,导致原发性副甲状腺症 (PHPT).
- 在临床上,它们可能类似于副甲状腺癌 (PC).
- 甲状腺危机是一种罕见但严重的PHPT并发症,涉及危及生命的高血症.
研究的目的:
- 报告一个巨型副甲状腺腺瘤的病例,呈现为副甲状腺危机.
- 为了突出GPA和PC之间的诊断相似之处.
- 为了强调缺乏病理学特征,使这些疾病在手术前区分开来.
主要方法:
- 一个77岁的妇女的病例报告,出现了和肌肉衰弱的症状.
- 生物化学评估显示了依赖甲状腺激素的高血症.
- 图像显示了较大的副甲状腺质量 (31x24毫米).
- 手术侧甲状腺切除术,然后进行组织学检查.
主要成果:
- 组织病理学证实了巨型副甲状腺腺瘤,排除了恶性瘤.
- 患者的表现模仿了副甲状腺癌的表现.
- 没有确定的临床,实验室或成像特征可以将GPA与PC区分开来.
结论:
- 巨型副甲状腺瘤可以出现副甲状腺危机,模仿副甲状腺癌.
- 由于临床和诊断特征重叠,在手术前区分GPA和PC仍然具有挑战性.
- 组织病理学分析对于确定诊断至关重要.
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