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Updated: Jul 19, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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Published on: September 15, 2018

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基因分析和管理家族高胆固醇血症血统与多基因变异:案例报告

Yu Han1,2,3, Lin Zhang1,2,3,4, Huimin Tao1,2,3

  • 1Affiliated Xuzhou Clinical College of Xuzhou Medical University, Xuzhou, China.

Medicine
|August 11, 2023
PubMed
概括

这项研究确定了家族性高胆固醇血症 (FH) 的多基因变异,包括LDLR,APOB和EPHX2基因. 整体外基组测序和遗传咨询对于诊断FH和指导受影响家庭至关重要.

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