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对侵袭状鼻的垂体瘤风险因素的分析

Bin Luo^1,2, Hecheng Ren¹, Yubo Wang¹

¹Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, China.

|August 11, 2023

概括

高分辨率CT有助于理解脑垂体瘤侵袭状鼻的情况. 瘤大小和Ki-67水平预测了入侵风险,为手术计划提供了信息.

科学领域:

神经外科神经外科
放射学放射学是一门学科.
内分泌学在内分泌学.

背景情况:

高分辨率计算机断层扫描 (HR-CT) 对于评估垂体瘤 (PNs) 以及它们与相邻结构的关系至关重要.
病理特征为PN生长模式提供了洞察力,但整合成像和病理学可能会改善外科规划的预测能力.

研究的目的:

通过HR-CT来研究垂体瘤和状鼻 (SS) 解剖学之间的关系.
识别预测PNSSS入侵的成像和病理因素.

主要方法:

分析了54名PN患者和52名志愿者的HR-CT图像.
在细分后,用ITK-SNAP软件计算了状鼻 (SS) 的体积.
与临床和病理数据相关的PN侵入性属性的比较分析.

主要成果:

与志愿者 (11.05毫升) 相比,PN组 (7.45毫升) 的SS体积明显较小 (P = .005).
在83.3%的PN患者中观察到压缩的细胞底,细胞后肺炎是常见的.
患有PN的男性患者的SS入侵率较高 (72.7%),与Ki-67抗原和瘤直径增加有关 (P < .05).

结论:

状鼻侵袭PNS受SS气动化类型和床形态的影响.
瘤最大直径 (>24.5毫米) 和Ki-67抗原水平 (>3.25%) 是SS入侵的重要风险因素.
这些发现有助于临床医生制定有效的治疗策略,用于垂体瘤.

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