在胎儿的异常血管环
A Savis1, C Oakley1, M P M Van Poppel2
1Department of Congenital Heart Disease, Evelina London Children's Hospital, Westminster Bridge Road, London, SE1 7EH, UK.
Pediatric cardiology
|August 11, 2023
概括
这项研究详细介绍了两名患有罕见左大动脉管血管环的胎儿,强调了动脉管道带位置在诊断压缩症状方面的重要性. 与右大动脉血管环相比,也发现了类似的关联.
科学领域:
- 心脏病学 心脏病学
- 医学遗传学 医学遗传学
- 胎儿医学 胎儿医学
背景情况:
- 血管环是影响大动脉的先天性异常.
- 左主动脉形异常比右主动脉形异常少见.
- 异常的右下关节动脉和右动脉管道可以导致复杂的血管环.
研究的目的:
- 描述两个胎儿的临床,心声学和遗传发现,其中两个胎儿具有特定的左主动脉血管环.
- 为了突出动脉管道带位置的临床意义.
- 为了比较左主动脉弧血管环与右主动脉弧血管环的关联.
主要方法:
- 案例系列呈现.
- 临床课程审查. 临床课程审查.
- 心声学评估. 心声学评估.
- 基因分析 (22q11.2微删除测试).
主要成果:
- 两个胎儿呈现左侧大动脉门,右侧动脉管和异常的右下关节动脉.
- 一个胎儿有22q11.2微切除;另一个胎儿在婴儿时就出现了症状.
- 记住了气管食道压缩症状,强调了管道带位置.
结论:
- 动脉导管带的位置对于诊断有压缩症状的左主动脉血管环至关重要.
- 左主动脉血管环可以与右主动脉血管环共享类似的临床关联.
- 对于受影响的胎儿和婴儿来说,早期识别和遗传评估很重要.
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