动脉旋转标记MRI用于脑瘤监测:我们真的需要脑血流图吗?
Wouter H T Teunissen1,2,3, Anna Lavrova4,5, Martin van den Bent6,7
1Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands. w.teunissen@erasmusmc.nl.
European radiology
|August 11, 2023
概括
动脉旋转标签 (ASL) perfusion MRI用于脑瘤监测可以简化. 非定量ASL-PWI和定量ASL-CBF显示高相关性和类似的准确性,这表明量化可能被遗漏.
科学领域:
- 神经成像是一种神经成像.
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 先进的MRI技术,如动脉脊柱标记 (ASL) perfusion MRI,用于大脑瘤监测.
- 评估瘤进展需要精确的输液测量.
研究的目的:
- 调查定量脑血流 (CBF) 与非定量ASL输液加权成像 (ASL-PWI) 测量之间的相关性.
- 评估ASL-CBF,ASL-PWI的诊断准确性,以及识别脑瘤进展的视觉评估.
主要方法:
- 分析了来自115名接受治疗的大脑瘤患者的ASL输液MRI数据.
- 感兴趣的区域 (ROI) 绘制在瘤和正常白质 (NAWM) 中.
- 使用皮尔森相关性评估ASL-CBF和ASL-PWI比率之间的相关性;使用AUC和视觉分类来确定诊断准确性.
主要成果:
- 在ASL-CBF比率和ASL-PWI比率之间发现了非常高的相关性 (0.96).
- 在ASL-CBF比率下,曲线下的面积 (AUC) 为0.76,在ASL-PWI比率下为0.72.
- 对增强病变的视觉评估显示诊断准确率为0.72.
结论:
- 在脑瘤监测中,定量ASL-CBF测量可能会被遗漏,因为与非定量ASL-PWI的高相关性和可比准确性.
- 视觉评估表明诊断准确度与ASL-CBF和ASL-PWI比率相似.
- 简化ASL评估可以减少常规临床实践中的复杂性.
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